miR-183-5p Promotes HCC Migration/Invasion via Increasing Aerobic Glycolysis
نویسندگان
چکیده
منابع مشابه
MiR-183 modulates multi-drug resistance in hepatocellular cancer (HCC) cells via miR-183-IDH2/SOCS6-HIF-1α feedback loop.
OBJECTIVE MiR-183 acts as an oncomiR and is usually upregulated in hepatocellular cancer (HCC). This study aims to study the association between miR-183 dysregulation and multi-drug resistance (MDR). Also, how it is dysregulated in HCC cells was investigated. MATERIALS AND METHODS The association between miR-183 and HIF-1α in HCC cell line BEL-7402 and the multidrug-resistant variant BEL-7402...
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1Department of Neurology, University Medical Center Göttingen, Robert-Koch-Str. 40, 37075 Göttingen, Lower-Saxony, Germany; 2DFG Cluster of Excellence Nanoscale Microscopy and Molecular Physiology of the Brain (CNMPB), University Medical Center Göttingen, Robert-Koch-Str. 40, 37075 Göttingen, Lower-Saxony, Germany; 3Department for Epigenetics and Systems Medicine in Neurodegenerative Diseases, ...
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ژورنال
عنوان ژورنال: OncoTargets and Therapy
سال: 2021
ISSN: 1178-6930
DOI: 10.2147/ott.s304117